Question3

=Text of the Question:= toc When //E. coli// ribosomes stall during protein synthesis, this may be a sign that the protein in the process of being translated is unrecoverable and should be destroyed. Draw a cartoon of the process by which the protein is tagged for destruction and what happens to it after beeing tagged. Include sufficient detail so that it is clear that you understand the process, especially how the translation apparatus is subverted to protein degradation. Cite appropriate literature sources.

=Diagram of Protein Destruction Pathway:Discussion of the Pathway:=

=Mechanism:= =**Relevant Literature:** = 3.1. [|Karzai, A. W., E. D. Roche, et al. (2000). "The SsrA-SmpB system for protein tagging, directed degradation and ribosome rescue." Nat Struct Mol Biol 7(6): 449-455.]